Tous les livres numériques de la collection "Methods & Principles in Medicinal Chemistry" - Wiley-VCH

78 Livre(s)
Télécharger le livre : Predictive Toxicology
Predictive Toxicology
Friedlieb Pfannkuch , Laura Suter-Dick
Tailored to the needs of scientists developing drugs, chemicals, cosmetics and other products this one-stop reference for medicinal chemists covers all the latest developments in the field of predictive toxicology and its applications in safety assessment. With a keen...

Editeur : Wiley-VCH
Parution : 2014-10-15
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

160,99 €
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Télécharger le livre : In vivo Models for Drug Discovery
In vivo Models for Drug Discovery
Michel Hamon , Rafael Maldonado , José Miguel Vela
This one-stop reference is the first to present the complete picture -- covering all relevant organisms, from single cells to mammals, as well as all major disease areas, including neurological disorders, cancer and infectious diseases. Addressing the needs of the...

Editeur : Wiley-VCH
Parution : 2014-07-31
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

172,91 €
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Télécharger le livre : Drug Metabolism Prediction
Drug Metabolism Prediction
Johannes Kirchmair
The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying...

Editeur : Wiley-VCH
Parution : 2014-06-26
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

190,74 €
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Télécharger le livre : Phosphodiesterases and Their Inhibitors
Phosphodiesterases and Their Inhibitors
Andrew S. Bell , Spiros Liras
Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major...

Editeur : Wiley-VCH
Parution : 2014-03-03
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

156,09 €
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Télécharger le livre : Natural Products in Medicinal Chemistry
Natural Products in Medicinal Chemistry
Stephen Hanessian
The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely...

Editeur : Wiley-VCH
Parution : 2013-12-18
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

179,30 €
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Télécharger le livre : Medicinal Chemistry Approaches to Personalized Medicine
Medicinal Chemistry Approaches to Personalized Medicine
Karen Lackey , Bruce Roth
Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues. ...

Editeur : Wiley-VCH
Parution : 2013-11-22
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

160,99 €
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Télécharger le livre : Scaffold Hopping in Medicinal Chemistry
Scaffold Hopping in Medicinal Chemistry
Nathan Brown
This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects. The first section serves as an introduction to the topic by describing the concept of...

Editeur : Wiley-VCH
Parution : 2013-11-06
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

160,99 €
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Télécharger le livre : Data Mining in Drug Discovery
Data Mining in Drug Discovery
Arnaud Gohier , Rémy D. Hoffmann , Pavel Pospisil
Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine....

Editeur : Wiley-VCH
Parution : 2013-09-25
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

178,82 €
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Télécharger le livre : Microwaves in Organic and Medicinal Chemistry
Microwaves in Organic and Medicinal Chemistry
Doris Dallinger , C. Oliver Kappe , Alexander Stadler
Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed, almost doubling the amount of chemical information with an additional volume. As in the predecessor, a short introductory...

Editeur : Wiley-VCH
Parution : 2013-03-19
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

220,60 €
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Télécharger le livre : Protein-Protein Interactions in Drug Discovery
Protein-Protein Interactions in Drug Discovery
Alexander Dömling
Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the...

Editeur : Wiley-VCH
Parution : 2013-01-02
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

178,82 €
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Télécharger le livre : Pharmacokinetics and Metabolism in Drug Design
Pharmacokinetics and Metabolism in Drug Design
Collectif
In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have...

Editeur : Wiley-VCH
Parution : 2012-09-13
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

137,15 €
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Télécharger le livre : Reactive Drug Metabolites
Reactive Drug Metabolites
Deepak Dalvie , Amit S. Kalgutkar , R. Scott Obach , Dennis A. Smith
Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largest pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite...

Editeur : Wiley-VCH
Parution : 2012-09-06
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

172,91 €
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Télécharger le livre : Bioisosteres in Medicinal Chemistry
Bioisosteres in Medicinal Chemistry
Nathan Brown
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical...

Editeur : Wiley-VCH
Parution : 2012-06-18
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

160,99 €
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Télécharger le livre : Protein-Ligand Interactions
Protein-Ligand Interactions
Holger Gohlke
Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a...

Editeur : Wiley-VCH
Parution : 2012-06-04
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

176,13 €
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Télécharger le livre : Antiviral Drug Strategies
Antiviral Drug Strategies
Erik De Clercq
By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses. It begins with a general discussion...

Editeur : Wiley-VCH
Parution : 2011-04-08
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

196,76 €
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Télécharger le livre : Virtual Screening
Virtual Screening
Christoph Sotriffer
Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both the small and large molecule are known, their interaction...

Editeur : Wiley-VCH
Parution : 2011-03-31
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

202,67 €
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Télécharger le livre : Protein Kinases as Drug Targets
Protein Kinases as Drug Targets
Michael Hamacher , Bert Klebl , Gerhard Müller
This timely guide to kinase inhibitor drug development is the first to cover the entire drug pipeline, from target identification to compound development and clinical application. Edited by the pioneers in the field, on the drug development side this ready reference...

Editeur : Wiley-VCH
Parution : 2011-03-16
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

141,32 €
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Télécharger le livre : Chemokine Receptors as Drug Targets
Chemokine Receptors as Drug Targets
Rob Leurs , Sergio A. Lira , Martine J. Smit
Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine research, the pharmaceutical industry has now begun to exploit this crucial signaling pathway for the development...

Editeur : Wiley-VCH
Parution : 2010-12-07
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

196,76 €
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Télécharger le livre : Prodrugs and Targeted Delivery
Prodrugs and Targeted Delivery
Jarkko Rautio
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational...

Editeur : Wiley-VCH
Parution : 2010-11-29
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

184,84 €
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Télécharger le livre : Aspartic Acid Proteases as Therapeutic Targets
Aspartic Acid Proteases as Therapeutic Targets
Arun K. Ghosh
In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular...

Editeur : Wiley-VCH
Parution : 2010-07-28
Collection : Methods & Principles in Medicinal Chemistry PDF, ePub

220,60 €
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