Dr. de Witte is a psychiatrist with a background in preclinical research in the fields of virology and immunology. She is an MD PhD interested in how the immune system plays a role in psychotic disorders. In parallel to her residencies in psychiatry, she started her own research group at the Brain Center Rudolf Magnus in Utrecht, the Netherlands investigating the prevalence and role of neuronal auto-antibodies and neurotropic pathogens in psychotic disorders. He research has resulted in a novel and distinctive research line studying the phenotype and function of microglia in psychotic disorders.