Téléchargez le livre : Iron Acquisition by the Genus Mycobacterium

Iron Acquisition by the Genus Mycobacterium

History, Mechanisms, Role of Siderocalin, Anti-Tuberculosis Drug Development

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Éditeur :

Springer


Collection :

SpringerBriefs in Molecular Science

Paru le : 2013-05-17



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Description

Iron Acquisition by the Genus Mycobacterium summarizes the early evidence for the necessity of iron in mycobacteria and the discovery of the mycobacterial siderophores mycobactin, carboxymycobactin, and exochelin. The structural characterization of the mycobacterial siderophores is described.  The genes so far identified as essential for iron acquisition and maintenance of an infection by pathogenic mycobacteria are discussed.  The potential role of siderocalin in iron gathering by M. tuberculosis is featured. Because new drugs for M. tuberculosis are needed, this brief also emphasizes the design of antibiotics that interfere with siderophore biosynthesis and the use of siderophore analogs and/or conjugates.
Pages
92 pages
Collection
SpringerBriefs in Molecular Science
Parution
2013-05-17
Marque
Springer
EAN papier
9783319003023
EAN EPUB
9783319003030
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
9
Taille du fichier
1546 Ko
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Prix
52,74 €

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