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This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume, leading neuroscientists from academia and industry provide a perspective of current research, both basic and...
Editeur :
Academic Press
Parution :
2010-09-21
epub sans DRM
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Delivery of therapeutic proteomics and genomics represent an important area of drug delivery research. Genomics and proteomics approaches could be used to direct drug development processes by unearthing pathways involved in disease pathogenesis where intervention may be...
Editeur :
Elsevier Science
Parution :
2010-09-09
epub sans DRM
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Angiogenesis (formation of new vessels from pre-existing ones) is a crucial early event in the process of tumor development. New vessels supply the tumor with nutrients that are needed for further local growth and enable distant metastases (Folkman 1995). Judah Folkman...
Editeur :
Springer
Parution :
2010-09-02
ePub
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The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial cells and pe- cytes, as well as inflammatory cells such as neutrophils, monocytes, macrophages, mast cells and...
Editeur :
Humana
Parution :
2010-09-02
ePub
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The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials guides drug development organizations in preparing and submitting an...
Editeur :
Wiley
Parution :
2010-08-03
PDF, ePub
Offre spéciale
-10%
180,95€
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Pharmaceutical and Biomedical Portfolio Management in a Changing Global Environment explores some of the critical forces at work today in the complex endeavour of pharmaceutical and medical product development. Written by experienced professionals, and including...
Editeur :
Wiley
Parution :
2010-08-03
Collection :
Wiley Series on Technologies for the Pharmaceutical Industry
PDF
Offre spéciale
-10%
121,95€
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In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular...
Editeur :
Wiley-VCH
Parution :
2010-07-28
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their...
Editeur :
Springer
Parution :
2010-07-28
Collection :
Current Cancer Research
ePub
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Everyone expects something from the drug industry. Physicians and patients, investors, regulators and administrators all have an active interest.Everyone wants to know what makes drugs 'work' medically and economically. Why are drugs so expensive? Is it the drug...
Editeur :
Academic Press
Parution :
2010-07-26
PDF, epub sans DRM
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Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug...
Editeur :
Academic Press
Parution :
2010-07-26
epub sans DRM
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"Dr. Paris has written an honest, balanced presentation of the ways in which psychiatric drugs are evaluated and prescribed. He highlights the complexity of the task, the limits of what is known and the mixed picture that research often produces. His conclusions are...
Editeur :
Wiley
Parution :
2010-07-06
PDF, ePub
Offre spéciale
-10%
50,95€
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The ultimate Canadian guide to prescription medication Over half of all Canadians take at least one prescription drug, but most of us know very little about the medication we're taking, including why we've been prescribed anything in the first place. Understanding...
Editeur :
For Dummies
Parution :
2010-06-28
PDF
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Born out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case...
Editeur :
Wiley-VCH
Parution :
2010-06-24
PDF, ePub
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Nitric Oxide (NO) is a pleitropic, ubiquitous modulator of cellular functions. Aryl nitrite and glyceryl trinitrate, representative intravasadilators, were introduced as therapeutic agents more than a century ago for relief from acute attacks of angina. The vasodilator...
Editeur :
Humana
Parution :
2010-06-16
ePub
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Energy Balance and Cancer, Epidemiology and Overview is the first in a series of monographs to address the multiple facets of the world wide pandemic of overweight and obesity and its relation to cancer. This volume, authored by leading experts in their perspective...
Editeur :
Springer
Parution :
2010-06-16
Collection :
Energy Balance and Cancer
ePub
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Protein kinase C (PKC), a family of serine-threonine kinases, rocketed to the forefront of the cancer research field in the early 1980’s with its identification as an effector of phorbol esters, natural products with tumor promoting activity. Phorbol esters had long...
Editeur :
Humana
Parution :
2010-06-10
Collection :
Current Cancer Research
ePub
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G protein-coupled receptors (GPCRs) are a large protein family of transmembrane receptors vital in dictating cellular responses. GPCRs are involved in many diseases, but are also the target of around half of all modern medicinal drugs. Shifting Paradigms inG Protein...
Editeur :
Wiley
Parution :
2010-05-25
PDF, ePub
Offre spéciale
-10%
177,95€
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Elsevier now offers a series of derivative works based on the acclaimed Meyler's Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing biomedical researcher and/or clinician. There has been significant progress...
Editeur :
Elsevier Science
Parution :
2010-04-19
epub sans DRM
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An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a...
Editeur :
Wiley
Parution :
2010-04-07
PDF
Offre spéciale
-9%
118,95€
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In spite of the development of various anticancer drugs, the therapy of cancer has remained challenging for decades. The current therapy of cancer is overwhelmed because of the inability to deliver therapeutics to all regions of a tumor in effective therapeutic...
Editeur :
Humana
Parution :
2010-03-20
Collection :
Cancer Drug Discovery and Development
ePub
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