Téléchargez le livre : Role of Transcription Factors in Gastrointestinal Malignancies

Role of Transcription Factors in Gastrointestinal Malignancies

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Springer


Paru le : 2018-03-27

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Description

This book illustrates the importance of transcription factors in gastrointestinal cancer progression and metastasis with regard to understanding the mechanism and target definition in drug discovery. Further, it describes the complex issues associated with cancer cell growth and metastasis. The respective chapters provide detailed information on the various types of transcription factors (NF-kB, HIF-1, STAT-3, E2F1, and Sp1) and gastric-associated cancers (esophagus, stomach, colorectal, liver and pancreatic cancers) in connection with specific functional studies like cell cycle, angiogenesis, migration, invasion and apoptosis. These transcription factors control the expression of several signaling pathways involved in tumor growth, making them ideal targets for gastrointestinal cancer therapy. In closing, the book provides comprehensive descriptions of the major challenges associated with gastrointestinal cancer therapy.
Pages
517 pages
Collection
n.c
Parution
2018-03-27
Marque
Springer
EAN papier
9789811067273
EAN PDF
9789811067280
Informations sur l'ebook
Nombre pages copiables
5
Nombre pages imprimables
51
Taille du fichier
11633 Ko
Prix
148,39 €

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