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Description
In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades.
Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.
Pages
768 pages
Collection
Methods & Principles in Medicinal Chemistry
Parution
2017-08-02
Marque
Wiley-VCH
EAN papier
9783527340866
EAN PDF
9783527699131

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
768
Taille du fichier
13578 Ko
Prix
304,05 €
EAN EPUB
9783527699148

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
768
Taille du fichier
8008 Ko
Prix
304,05 €