Téléchargez le livre : Pharmacophores and Pharmacophore Searches
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Description
This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research.
Starting with an introductory historical overview, the authors move on to discuss ligand-based approaches, including 3D pharmacophores and 4D QSAR, as well as the concept and application of pseudoreceptors. The next section on structure-based approaches includes pharmcophores from ligand-protein complexes, FLIP and 3D protein-ligand binding interactions. The whole is rounded off with a complete section devoted to applications and examples, including modeling of ADME properties.
With its critical evaluation of pharmacophore-based strategies, this book represents a valuable aid for project leaders and decision-makers in the pharmaceutical industry, as well as pharmacologists, and medicinal and chemists.
Pages
395 pages
Collection
Methods & Principles in Medicinal Chemistry
Parution
2006-12-13
Marque
Wiley-VCH
EAN papier
9783527312504
EAN PDF
9783527608720
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
395
Taille du fichier
20183 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
174,02 €

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