Téléchargez le livre : Chirality in Drug Research
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Description
Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals.
The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report previously unpublished data.
In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution of racemic mixtures in preparative chromatography are outlined in separate chapters. For the section on qualitative and quantitative analysis, enantioselective chromatographic methods are presented as well as optical methods and CE-MS, while the final section deals with the pharmacology, pharmacokinetics and metabolic aspects of chiral drugs, devoting whole chapters to stereoselective drug binding and modeling chiral drug-receptor interactions.
With its unique industry-relevant aspects, this is a must for medicinal and pharmaceutical chemists.
Pages
370 pages
Collection
Methods & Principles in Medicinal Chemistry
Parution
2007-09-24
Marque
Wiley-VCH
EAN papier
9783527310760
EAN PDF
9783527608713
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
370
Taille du fichier
6103 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
225,72 €

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