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Description
Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The "epigenome" is a parallel to the word "genome," and refers to the overall epigenetic state of a cell. Cancer and stem cell research have gradually focused attention on these genome modifications. The molecular basis of epigenetics involves modifications to DNA and the chromatin proteins that associate with it. Methylation, for example, can silence a nearby gene and seems to be involved in some cancers.

Epigenetics is beginning to form and take shape as a new scientific discipline, which will have a major impact on Medicine and essentially all fields of biology. Increasingly, researchers are unearthing links between epigenetics and a number of diseases.

Although in recent years cancer has been the main focus of epigenetics, recent data suggests that epigenetic plays a critical role in psychology and psychopathology. It is being realized that normal behaviors such as maternal care and pathologies such as Schizophrenia and Alzheimer's might have an epigenetic basis. It is also becoming clear that nutrition and life experiences have epigenetic consequences.

Discover more online content in the Encyclopedia of Molecular Cell Biology and Molecular Medicine.
Pages
1254 pages
Collection
Advances in Molecular Biology and Medicine
Parution
2012-10-02
Marque
Wiley-Blackwell
EAN papier
9783527326822
EAN PDF
9783527668618
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
1254
Taille du fichier
11827 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
392,41 €
EAN EPUB
9783527668625
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
1254
Taille du fichier
31969 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
392,41 €

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