GM3 Signaling

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Éditeur :

Springer


Paru le : 2020-07-10

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Description
This book reviews recent progress in understanding of the signaling and biochemistry of GM3 ganglioside in eukaryotic cells. GM3 is the simplest of the gangliosides and the precursor of other gangliosides. It is expressed in the outer leaflet of plasma cell membranes and has roles in the recognition, interaction, binding, adhesion, and motility of cells. In addition, GM3 has been documented to have functional roles in cell migration, proliferation, senescence, and apoptosis. The full range of topics of interest are addressed in the book. The early chapters discuss the synthesis of GM3, its molecular localization in cells, and its basic function as an interacting molecule. The ways in which GM3 exerts its effects via various growth factor receptors are fully explored. Current knowledge of the part played by GM3 in health and disease is discussed in depth. For example, its roles in preventing inflammation, inhibiting tumor angiogenesis and tumor growth, and suppressing arthritis arehighlighted, and attention drawn to the significance of GM3 as a driver of impaired wound healing in diabetics. The book will be of interest to all who want a comprehensive update on research in this field.
Pages
138 pages
Collection
n.c
Parution
2020-07-10
Marque
Springer
EAN papier
9789811556517
EAN PDF
9789811556524

Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
13
Taille du fichier
4372 Ko
Prix
147,69 €
EAN EPUB
9789811556524

Informations sur l'ebook
Nombre pages copiables
1
Nombre pages imprimables
13
Taille du fichier
12800 Ko
Prix
147,69 €

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