Nrf2 and its Modulation in Inflammation



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Éditeur :

Springer


Collection :

Progress in Inflammation Research

Paru le : 2020-05-21



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Description

Nrf2, a transcription factor that mediates transcriptional responses to oxidative and xenobiotic stresses, plays a central role in cellular protection against internal or external toxins. Defects in Nrf2 and the relevant regulatory pathways are associated with a number of pathologies including inflammation, respiratory diseases, cardiovascular dysfunctions, metabolic syndrome and diabetes, neurodegeneration, and cancer. This book comprehensively reviews the up-to-date discoveries for the roles of Nrf2 in several human diseases in the context of inflammation. In particular, the molecular mechanisms that mediate the functions of Nrf2 and its interacting network in inflammation and pathogenesis are explicated. In addition, the research and therapeutic applications of Nrf2-targeting compounds in different diseases were summarized. This book is expected to be a valuable reference for worldwide researchers conducting both mechanistic and therapeutic studies of Nrf2 and relevant factors.
   
Pages
205 pages
Collection
Progress in Inflammation Research
Parution
2020-05-21
Marque
Springer
EAN papier
9783030445973
EAN PDF
9783030445997

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
20
Taille du fichier
7834 Ko
Prix
94,94 €
EAN EPUB
9783030445997

Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
20
Taille du fichier
8602 Ko
Prix
94,94 €