Target Discovery and Validation

Methods and Strategies for Drug Discovery

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Éditeur :

Wiley-VCH


Collection :

Methods & Principles in Medicinal Chemistry

Paru le : 2019-11-07



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Description
The modern drug developers? guide for making informed choices among the diverse target identification methods

Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling.

Throughout, the authors highlight a range of diverse approaches, and target validation studies reveal how these methods can support academic and drug discovery scientists in their target discovery and validation research. This resource:

-Offers a guide to identifying and validating targets, a key enabling technology without which no new drug development is possible
-Presents the information needed for choosing the appropriate assay method from the ever-growing range of available options
-Provides practical examples from recent drug development projects, e. g. in kinase inhibitor profiling

Written for medicinal chemists, pharmaceutical professionals, biochemists, biotechnology professionals, and pharmaceutical chemists, Target Discovery and Validation explores the current methods for the identification and validation of drug targets in one comrpehensive volume. It also includes numerous practical examples.
Pages
400 pages
Collection
Methods & Principles in Medicinal Chemistry
Parution
2019-11-07
Marque
Wiley-VCH
EAN papier
9783527345298
EAN PDF
9783527818259

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
400
Taille du fichier
10353 Ko
Prix
166,90 €
EAN EPUB
9783527818266

Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
400
Taille du fichier
15913 Ko
Prix
166,90 €