Téléchargez le livre : Death Receptors and Cognate Ligands in Cancer

Death Receptors and Cognate Ligands in Cancer

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Éditeur :

Springer


Collection :

Results and Problems in Cell Differentiation

Paru le : 2010-03-12

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Description
Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by corresponding death ligands. Many complex signaling pathways are activated and apoptosis is the final result of a complex biochemical cascade of events. Besides their role in the induction of cell death, evidence now exists that death receptors are able to activate several non-apoptotic signaling pathways which, depending on cellular context, may lead to apoptosis resistance, secretion of pro-inflammatory proteins, proliferation and invasive growth of cancer cells. This book looks at the molecular basis of death receptor signaling and the role of death receptors in cancer development.
Pages
280 pages
Collection
Results and Problems in Cell Differentiation
Parution
2010-03-12
Marque
Springer
EAN papier
9783642030444
EAN EPUB
9783642030451
Informations sur l'ebook
Nombre pages copiables
2
Nombre pages imprimables
28
Taille du fichier
2611 Ko
Prix
241,99 €

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